A mechanism of cooling hot tumors: lactate attenuates inflammation in dendritic cells [EGR1-KO]. A mechanism of cooling hot tumors: lactate attenuates inflammation in dendritic cells [EGR1-KO]

We assessed the role of early growth response protein 1 (EGR1) in dendritic cells. Overall design: We performed microarray analyses using bone marrow-derived dendritic cells (BMDCs) from WT and EGR1-deficient mice.本研究探讨了早期生长应答蛋白1（early growth response protein 1，EGR1）在树突状细胞中的功能作用。实验设计概述：本研究采用来自野生型（wild type，WT）与EGR1缺陷小鼠的骨髓来源树突状细胞（bone marrow-derived dendritic cells，BMDCs）进行基因芯片分析。