Superficial spreading melanoma - Female, 26 - Tissue image [6260730021895861]

This is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 26Clinical description: Brown lesion of skin of lower limb with dimensions 0,9 x 0,8 x 0,1 cm.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: NEVI AND MELANOMASDiagnosis: Superficial spreading melanomaResult of the histopathological examination: Superficial spreading melanoma: epithelioid cells, Clark III, Breslow 1 mm, Mitotic index: 1 mitosis/1 mm2, TILs NON-BRISK. PRAME+, HMB45+, Ki-67 5%.Sample:Material: FFPECollecting method: Excision of lesionsTopography: SKINOrgan: SKINTissue: Skin of lower limbType of staining: positive/IHCStaining: Not applicableAntibody: Ki67+HMB45Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）采集并存入ZMDL-GUMED数据库的皮肤组织样本病理组织学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪以20倍放大倍率采集，并存储为DICOM格式。

以下为患者、样本及诊断的详细信息：
### 患者信息
年龄：26岁
临床描述：下肢皮肤褐色皮损，尺寸为0.9×0.8×0.1 cm
性别：女
诊断分类标准：ICD-O_3.2
分类编码：NEVI AND MELANOMAS（痣与黑素瘤）
诊断：浅表播散性黑素瘤
病理检查结果：浅表播散性黑素瘤（上皮样细胞型），Clark分级Ⅲ级，Breslow厚度为1mm，核分裂象指数：1个核分裂/每平方毫米，肿瘤浸润淋巴细胞（Tumor-Infiltrating Lymphocytes, TILs）为非活跃型（NON-BRISK）。免疫组化标记结果：PRAME阳性、HMB45阳性，Ki-67增殖指数为5%。

### 样本信息
样本材质：福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）
采集方式：病灶切除术
病变部位：下肢皮肤
所属器官：皮肤
采集组织：下肢皮肤组织
染色类型：免疫组化（IHC）阳性染色
染色方式：不适用
所用抗体：Ki67+HMB45

### 成像技术与设备
成像设备：Pannoramic 250 3DHistech
镜头放大倍数：20倍
数据来源机构：格但斯克医科大学