Bulk RNA-sequencing in Ldlr-/- or Ch25h-/-;Ldlr-/- peritoneal macrophages treated with LPS. Bulk RNA-sequencing in Ldlr-/- or Ch25h-/-;Ldlr-/- peritoneal macrophages treated with LPS

Here we study the effect of LPS in the transcriptome of thioglycollate-elicited peritoneal macrophages isolated from Ldlr knock out and Ch25h;Ldlr double knock out mice Overall design: mRNA profiles from thioglycollated-elicited peritoneal macrophages isoaltes from LDLR KO CH25H;LDLR DKO mice

本研究旨在探讨脂多糖（Lipopolysaccharide, LPS）对源自低密度脂蛋白受体（Ldlr）敲除小鼠及胆固醇25-羟化酶（Ch25h）与Ldlr双敲除小鼠的硫乙醇酸盐诱导腹腔巨噬细胞转录组（transcriptome）的影响。实验设计：采集源自Ldlr敲除、Ch25h;Ldlr双敲除小鼠的硫乙醇酸盐诱导腹腔巨噬细胞分离物的mRNA转录谱。