Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2
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Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2 Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... Authors: Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. Deposit date: 2022-10-26 Release date: 2023-05-17 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
与乙酰化赖氨酸12和赖氨酸16的组蛋白H4核小体(H4K12acK16ac nucleosome)结合的CREB结合蛋白(CREB-binding protein, CBP)催化核心的冷冻电镜(Cryo-Electron Microscopy, Cryo-EM)结构,2类 数据集描述:CREB结合蛋白、180聚体DNA、组蛋白H2A 1-B/E型…… 作者:Kikuchi M、Morita S、Wakamori M、Shin S、Uchikubo-Kamo T、Shirouzu M、Umehara T 提交日期:2022-10-26 发布日期:2023-05-17 最后修改日期:2024-10-16 实验方法:电子显微镜(分辨率4.5埃) 引用文献:《通过p300/CBP传播组蛋白乙酰化的表观遗传机制》,*Nat Commun*,第14卷,2023年



