Inflammasome Signaling and Impaired Vascular Health in Psoriasis

De-identified RNA sequencing of whole blood in psoriasis and control participants Overall design: Cross-sectional comparison of disease (psoriasis) vs. control. We report the comparison in the whole blood transcriptome inflammatory signature by RNA sequencing in psoriasis compared to control individuals. We find the inflammasome signaling pathway as the highest differentially expressed.

本数据集包含银屑病患者与健康对照个体的全血去标识化RNA测序（RNA sequencing）数据。实验设计概况：采用横断面设计对比银屑病患者与健康对照人群。本研究通过RNA测序，对银屑病患者与健康对照个体的全血转录组炎症特征进行对比，并报告相关分析结果。研究发现炎症小体信号通路（inflammasome signaling pathway）为差异表达最显著的通路。