Data_Sheet_1_Research Trends and Hotspots on Herpes Zoster: A 10-Year Bibliometric Analysis (2012–2021).DOCX

PurposeHerpes zoster infection, with its considerable burden to individuals and society, remains a challenge around the world. However, to the knowledge of the authors, little bibliometric quantitative or qualitative analysis has been carried out to evaluate herpes zoster research. This study aimed to use a bibliometric analysis to evaluate current publication trends and hotspots on herpes zoster research worldwide, in order to advance research in this field.MethodsRelevant publications from January 2012 to December 2021 were collected from the Web of Science Core Collection database. Citespace (V5.8.R3) was used to analyze the research points, including publication countries, institutions and authors, cited author, cited reference and their clustering, and keyword co-occurrence, and burst keyword to acquire research trends and hotspots.ResultsA total of 9,259 publications were obtained, with a steady increase in the number of annual publications during the decade. Articles were the main type of publication. The United States is the leading country in this research, and the University of Colorado has the highest influence in this field. Oxman is the most representative author, with a main research interest in herpes zoster vaccines. The top five cited authors' publications focused on herpes zoster vaccines, molecular mechanisms, and postherpetic neuralgia. A co-citation map resulted 19 main clusters, and revealed that vaccines, postherpetic neuralgia, treatments, varicella zoster virus and its mechanisms, and epidemiology of herpes zoster were the current research focus after clustering co-cited publications. Human herpesviruses, antiviral prophylaxis, rheumatoid arthritis, recombinant zoster vaccine, varicella vaccination and postherpetic neuralgia were the top clusters after co-occurrence keywords analysis. Moreover, burst keywords detection showed that the subunit vaccine was the new hotspot in the field of herpes zoster.ConclusionThis bibliometric study defined the overall prospects in the field of herpes zoster and provided valuable instruction for the ongoing research. The keyword “subunit vaccine” indicated that a vaccine for herpes zoster prevention was the hotspot. Efforts to prevent varicella zoster virus infection will be essential to improve herpes zoster outcomes.

目的带状疱疹感染，因其对个人及社会造成的巨大负担，全球范围内仍是一项挑战。然而，据作者所知，迄今为止，关于带状疱疹的研究鲜有进行过文献计量学的定量或定性分析以评估其研究进展。本研究旨在运用文献计量分析法，对全球范围内带状疱疹研究的当前出版趋势和热点进行评估，以促进该领域的研究发展。方法自2012年1月至2021年12月，从《科学引文索引》核心合集数据库中收集相关出版物。采用Citespace（V5.8.R3）对研究点进行分析，包括出版国家、机构及作者、被引作者、被引文献及其聚类，以及关键词共现和突发关键词，以获取研究趋势和热点。结果共获得9,259篇出版物，十年间年度出版数量稳步增长。文章是主要的出版类型。美国在该研究领域处于领先地位，科罗拉多大学在该领域具有最高的影响力。Oxman是最具代表性的作者，其主要研究方向为带状疱疹疫苗。被引用次数最多的五位作者的研究成果集中在带状疱疹疫苗、分子机制和带状疱疹后神经痛等方面。共引文献图显示，聚类共引文献后形成了19个主要聚类，揭示了疫苗、带状疱疹后神经痛、治疗方法、水痘-带状疱疹病毒及其机制以及带状疱疹的流行病学是当前研究的焦点。人类疱疹病毒、抗病毒预防、类风湿性关节炎、重组带状疱疹疫苗、水痘疫苗接种和带状疱疹后神经痛是关键词共现分析后的主要聚类。此外，突发关键词检测显示，亚单位疫苗是该领域的新热点。结论本项文献计量学研究明确了带状疱疹领域的发展前景，并为正在进行的研究提供了宝贵的指导。关键词“亚单位疫苗”表明，针对带状疱疹预防的疫苗是研究的热点。努力预防水痘-带状疱疹病毒感染对于改善带状疱疹的预后至关重要。