Integrated Exome-seq analysis of tumor thrombus

We prospectively enrolled 83 patients with a renal mass and TT scheduled to undergo surgical resection. To accurately integrate genomic and transcriptomic findings and enable histological co-registration, simultaneous isolation of DNA and RNA was performed from individual samples characterized histologically through immediately flanking sectionsEGA study EGAS00001005511本研究前瞻性入组83例伴肾占位及瘤栓（Tumor Thrombus，TT）、拟接受手术切除的患者。为精准整合基因组与转录组学数据并实现组织学共配准，研究人员从经紧邻组织切片完成组织学鉴定的单个样本中同步分离DNA与RNA。本研究属于EGA研究EGAS00001005511。