Expression data of hAEC, hAFSC and hBMSC before and after osteogenic induction in vitro

The in vitro osteogenic differentiation of hAEC, hAFSC and hBMSC have been reported.The final tissue-forming potential of all three cell types may vary in terms of different anatomical origin and molecular response to osteogenic induction. We used microarrays to detail the global genes expression profiles of hAEC, hAFSC and hBMSC before and after osteogenic induction in vitro. Global gene expression profiles of hAECs, hBMSCs and hAFMSCs were evaluated before and after 7-day osteogenic induction in vitro. Samples were subjected to gene expression analysis using the Affymetrix human HTA2.0 microarray.

已有研究报道人羊膜上皮细胞（hAEC）、人羊水干细胞（hAFSC）以及人骨髓间充质干细胞（hBMSC）的体外成骨分化情况。该三类细胞的最终组织形成潜能可能因解剖来源差异以及对成骨诱导的分子应答不同而存在差异。本研究通过基因微阵列（microarray）技术，详细解析了hAEC、hAFSC与hBMSC在体外成骨诱导前后的全基因表达谱。本研究同时评估了hAECs、hBMSCs与hAFMSCs在体外接受7天成骨诱导前后的全基因表达谱。所有样本均采用Affymetrix人类HTA2.0基因微阵列开展基因表达分析。