Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet in P53 -/- mice

Gene expression for genes differentially expressed between early vs. late tumor onset and high fat diet (HFD) vs. low fat diet (LFD) in P53 -/- mice. 4 HFD early tumor onset, 7 HFD late tumor onset, 4 HFD to LFD switch with early tumor onset, 6 HFD to LFD switch with late tumor onset, 4 LFD early tumor onset, 7 LFD late tumor onset, 5 LFD to HFD switch with early tumor onset, 4 LFD to HFD switch with late tumor onset本数据集涵盖P53基因敲除（P53 -/-）小鼠中，肿瘤早发与晚发、高脂饮食（HFD）与低脂饮食（LFD）两类对比条件下的差异表达基因的基因表达数据。具体分组及对应样本量如下：高脂饮食+早发肿瘤组4例、高脂饮食+晚发肿瘤组7例、由高脂饮食切换为低脂饮食且早发肿瘤组4例、由高脂饮食切换为低脂饮食且晚发肿瘤组6例、低脂饮食+早发肿瘤组4例、低脂饮食+晚发肿瘤组7例、由低脂饮食切换为高脂饮食且早发肿瘤组5例、由低脂饮食切换为高脂饮食且晚发肿瘤组4例。