Seroprevalence of Trypanosoma cruzi infection in blood donors in the extreme South of Brazil

ABSTRACT Background: We aimed to evaluate the seroprevalence of Chagas disease among blood donors in southern Rio Grande do Sul, Brazil. Methods: The study was conducted from 2010 to 2019 based on data registered by the Hemocentro Regional de Pelotas, Rio Grande do Sul. Results: There were 106,320 blood donations, and the discard rate of blood bags, either due to positive reactions to anti-T. cruzi antibodies or inconclusive results was 0.27% (283 bags). Conclusions: The usage of methods that enable the safe identification of donors with positive serology for Chagas disease is fundamental to ensure transfusional safety.

摘要
研究背景：本研究旨在评估巴西南里奥格兰德州南部献血人群中恰加斯病（Chagas disease）的血清流行率。
研究方法：本研究于2010年至2019年间开展，数据源自南里奥格兰德州佩洛塔斯区域血液中心（Hemocentro Regional de Pelotas）的登记存档资料。
研究结果：本研究共纳入106320例献血，其中因抗克氏锥虫（Trypanosoma cruzi，T. cruzi）抗体检测反应阳性或检测结果不确定而废弃的血袋废弃率为0.27%（共计283袋）。
研究结论：采用可安全识别恰加斯病血清学阳性献血者的检测方法，是保障输血安全的必要前提。