Immunization of a wild koala population with a recombinant Chlamydia pecorum Major Outer Membrane Protein (MOMP) or Polymorphic Membrane protein (PMP) based vaccine: new insights into immune response, protection and clearance

We assessed the effects of two different single-dose anti-Chlamydia pecorum (C. pecorum) vaccines (containing either Major Outer Membrane Protein (3MOMP) or Polymorphic Membrane Protein (Pmp) as antigens) on the immune response of a group of wild koalas using ELISA, RT-qPCR and phylogeny analysis.

本研究采用酶联免疫吸附试验（ELISA）、实时荧光定量聚合酶链式反应（RT-qPCR）及系统发育分析，评估了两种不同单剂抗兽类衣原体（Chlamydia pecorum，简称C. pecorum）疫苗（分别以主要外膜蛋白（Major Outer Membrane Protein，3MOMP）和多态性膜蛋白（Polymorphic Membrane Protein，Pmp）作为抗原）对一组野生考拉免疫应答的影响。