Whole genome profiling of whole liver lysates of vehicle and Sorafenib-treated iAST mice. Mus musculus

Analysis of changes in gene expression upon Sorafenib treatment. Looking for candidates, that could potentially be up- or down-regulated upon Sorefanib treatment. Overall design: Total RNA were optained from whole liver lysates of vehicle 14d-, Sorafenib 14d- and LT Sorafenib-treated iAST mice

本研究旨在分析索拉非尼（Sorafenib）处理后的基因表达变化，筛选经该药物处理后可能发生上调或下调的候选基因。实验整体设计：从溶媒对照14天处理组、索拉非尼14天处理组以及长期索拉非尼（LT Sorafenib）处理的iAST小鼠的全肝裂解物中提取总RNA。