Pooled measures for associations between the <i>UCP1</i> -3826A/G, <i>UCP2</i> -866G/A, <i>UCP2</i> Ala55Val, <i>UCP2</i> Ins/Del and <i>UCP3</i> -55C/T polymorphisms and susceptibility to T2DM.

Where significant heterogeneity was detected (I2>50%), the DerSimonian and Laird random effect model (REM) was used to calculate OR (95% CI) for each individual study and for the pooled effect; where heterogeneity was not significant, the fixed effect model (FEM) was used for this calculation. *Stratification analysis was only performed for Europeans for the UCP2 Ins/Del polymorphism (allele contrast model), since only one study of Asians was identified.当检测到显著异质性（I²>50%）时，采用德西蒙尼-莱尔德随机效应模型（DerSimonian and Laird random effect model，REM）计算各项独立研究的比值比（Odds Ratio，OR）及合并效应的95%置信区间（95% Confidence Interval，95% CI）；当异质性无统计学意义时，则采用固定效应模型（fixed effect model，FEM）进行上述计算。 *针对解偶联蛋白2（UCP2）插入/缺失（Ins/Del）多态性的等位基因对比模型（allele contrast model），仅对欧洲人群开展了分层分析（Stratification analysis），因仅检索到1项亚洲人群相关研究。