Dataset related to article "Multidisciplinary Tumor Board in the Management of Patients with Colorectal Liver Metastases: A Single-Center Review of 847 Patients "

This record contains raw data related to article “Multidisciplinary Tumor Board in the Management of Patients with Colorectal Liver Metastases: A Single-Center Review of 847 Patients" Abstract There is still debate over how reviewing oncological histories and addressing appropriate therapies in multidisciplinary team (MDT) discussions may affect patients' overall survival (OS). The aim of this study was to describe MDT outcomes for a single cancer center's patients affected by colorectal liver metastases (CRLMs). From 2010 to 2020, a total of 847 patients with CRLMs were discussed at our weekly MDT meeting. Patients' characteristics and MDT decisions were analyzed in two groups: patients receiving systemic therapy (ST) versus patients receiving locoregional treatment (LRT). Propensity-score matching (PSM) was run to reduce the risk of selection bias. The median time from MDT indication to treatment was 27 (IQR 13-51) days. The median OS was 30 (95%CI = 27-34) months. After PSM, OS for patients undergoing LRT was 51 (95%CI = 36-64) months compared with 15 (95%CI = 13-20) months for ST patients (<em>p</em> &amp;lt; 0.0001). In this large retrospective study, the MDT discussions were useful in providing the patients with all available locoregional options.本数据集收录与论文《结直肠癌肝转移多学科团队诊疗管理：847例患者单中心回顾性研究》摘要相关的原始数据。目前学界对于多学科团队（Multidisciplinary Team, MDT）讨论中回顾肿瘤病史并制定合理治疗方案是否会影响患者总生存期（Overall Survival, OS）仍存在争议。本研究旨在描述本院收治的结直肠癌肝转移（Colorectal Liver Metastases, CRLMs）患者的MDT诊疗结局。2010年至2020年间，共计847例CRLMs患者在我院每周一次的MDT会议中接受病例讨论。研究将患者分为系统治疗（Systemic Therapy, ST）组与局部区域治疗（Locoregional Treatment, LRT）组，对患者基线特征及MDT诊疗决策进行分析。为降低选择偏倚风险，本研究采用倾向得分匹配（Propensity-Score Matching, PSM）方法。从MDT审议病例至启动治疗的中位时间为27天（四分位距13~51天）。所有患者的中位总生存期为30个月（95%置信区间27~34）。经PSM校正后，接受LRT的患者中位OS为51个月（95%置信区间36~64），而接受ST的患者中位OS为15个月（95%置信区间13~20），组间差异具有显著统计学意义（p < 0.0001）。本项大型回顾性研究表明，MDT讨论可帮助患者获取所有可用的局部区域治疗方案。