Additional file 4: of Survival marker genes of colorectal cancer derived from consistent transcriptomic profiling

Table S4. Validation of the survival data done in an independent set of samples taken from The Cancer Genome Atlas (TCGA), that included 269 colorectal carcinomas with survival information and RNA-seq global expression profiling. The table includes the KM p-values and HR of the genes that were validated from the top-10 survival marker genes previously found presented in Table 3. Of the top-10 for the case of up-regulation associated with poor survival, 7 were validated (PTPN14, LAMP5, TM4SF1, LCA5, CSGALNACT2, SLC2A3 and GADD45B). Of the top-10 found for down-regulation associated with poor survival, 6 genes were validated (EPHB2, DUS1L, NUAK2, FANCC, MYB and CHDH). (XLSX 51 kb)

表S4。本表格针对取自癌症基因组图谱（The Cancer Genome Atlas, TCGA）的独立样本队列中的生存数据开展验证，该队列纳入269例携带生存信息及全转录组RNA测序表达谱数据的结直肠癌样本。本表格收录了此前在表3中鉴定出的前10位生存标记基因中得到验证的基因的KM（Kaplan-Meier）检验P值与风险比（Hazard Ratio, HR）。在与不良预后相关的上调基因前10位列表中，有7个基因通过验证（PTPN14、LAMP5、TM4SF1、LCA5、CSGALNACT2、SLC2A3及GADD45B）；在与不良预后相关的下调基因前10位列表中，共有6个基因通过验证（EPHB2、DUS1L、NUAK2、FANCC、MYB及CHDH）。（XLSX格式，文件大小51 KB）