Supporting data for " Block Co-polymer Metal Organic Cage Micelles: Towards Unimolecular, Atomically Precise and Highly Addressable Composite Nanoparticles"

The dataset includes original record of experimental protocols, raw data, and analyzed figures for thesis. It's also accompanied with research slides from our regular group meeting. The thesis describes the synthesis of atomcially precise nanoparticles and their applications in nanomedicine, which is assembled via a directed, stepwise strategy by integrating metal-organic polydedral complexes and sequence defined peptoids. The dataset contains a variety of original data that support the thesis. For example, the NMR and LC-MS help to identify the small molecular, polymers and peptoids. The Uv-vis can characterize the structure integrity of metal-organic complexes. DLS and TEM are used to measure their sizes and morphologies. Native mass spectroscopy can identify the atom-precision features of the nanoparticle. Fluorescence is used to measure the critical micelle concentration and fluorescence resonance energy transfer. Research slides regarding to the projects are also shared.本数据集包含用于学位论文的实验方案原始记录、原始实验数据及分析后图表，同时附带课题组常规组会使用的项目研究汇报幻灯片。本学位论文围绕原子级精确纳米颗粒的合成及其在纳米医学中的应用展开研究，该纳米颗粒通过整合金属有机多面体配合物与序列定制类肽，采用定向分步组装策略制得。本数据集包含多类支撑该论文的原始实验数据：例如，核磁共振波谱（Nuclear Magnetic Resonance, NMR）与液相色谱-质谱联用（Liquid Chromatography-Mass Spectrometry, LC-MS）可用于鉴定小分子、聚合物及类肽的结构；紫外-可见吸收光谱（Ultraviolet-Visible Spectroscopy, UV-Vis）可表征金属有机配合物的结构完整性；动态光散射（Dynamic Light Scattering, DLS）与透射电子显微镜（Transmission Electron Microscopy, TEM）用于测定纳米颗粒的尺寸与形貌；Native质谱（Native Mass Spectrometry）可鉴定纳米颗粒的原子级精确结构特征；荧光光谱（Fluorescence Spectroscopy）可用于测定临界胶束浓度与荧光共振能量转移（Fluorescence Resonance Energy Transfer, FRET）效应。本数据集还共享了与该研究项目相关的组会汇报幻灯片。