Prevalence of multiple sclerosis in Goiânia, Goiás, Brazil

ABSTRACT Multiple sclerosis (MS) prevalence, in some cities in Brazil, was estimated and was found to range from 0.75 to 30.7/100,000. The reasons for such a large variation in rates of prevalence are not clear, but environment and genetics help to explain this phenomenon. Methods: A cross-sectional study using three sources of case ascertainment to estimate the prevalence of MS in the city of Goiânia in December, 2015. Results: A total of 318 MS patients was found after removing overlapping sources. The prevalence of MS was 22.4/100,000 population. Conclusion: Our study was the first in Goiás and the third in the midwest region, and we found a great increase in the prevalence of MS in the region. It is necessary to perform other studies using the same methodology for a more accurate evaluation of the true prevalence of MS in Brazil.

摘要：针对巴西部分城市的多发性硬化症（multiple sclerosis, MS）患病率展开估算，结果显示其区间为0.75~30.7/10万。该患病率存在显著差异的原因尚未明确，但环境与遗传因素可部分解释这一现象。
方法：本研究采用三种病例确认渠道开展横断面研究，以估算2015年12月戈亚尼亚市的多发性硬化症患病率。
结果：剔除重叠病例来源后，共纳入318例多发性硬化症患者，该市患病率为22.4/10万人口。
结论：本研究为戈亚斯州内首例、巴西中西部地区第三项相关研究，结果显示该区域多发性硬化症患病率已出现明显升高。未来需采用相同研究方法开展更多研究，以更精准地评估巴西多发性硬化症的真实患病率。