Prediction of designer-recombinases for DNA editing with generative deep learning. RecGen
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https://www.ncbi.nlm.nih.gov/bioproject/PRJEB57361
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资源简介：
Sequence data from "Prediction of designer-recombinases for DNA editing with generative deep learning" publication. Tyrosine site-specific recombinase gene sequences. Recombinases were produced with directed evolution and sequenced with PacBio HiFi. Some of the evolutions of the recombinases sequences in this dataset were published in the following publications: https://doi.org/10.1126/science.1141453 https://doi.org/10.1038/nbt.3467 https://doi.org/10.1093/nar/gkz1078 https://doi.org/10.1038/s41467-022-28080-7
本数据集源自论文《基于生成式深度学习预测DNA编辑用定制重组酶》（"Prediction of designer-recombinases for DNA editing with generative deep learning"）。
数据集包含酪氨酸位点特异性重组酶（Tyrosine site-specific recombinase）基因序列。
该数据集收录的重组酶通过定向进化技术制备，并经PacBio HiFi测序。
本数据集内部分重组酶序列的进化研究已发表于以下论文：
https://doi.org/10.1126/science.1141453
https://doi.org/10.1038/nbt.3467
https://doi.org/10.1093/nar/gkz1078
https://doi.org/10.1038/s41467-022-28080-7
创建时间：
2022-11-15
