Transcriptional profile of bone marrow mature neutrophils. Transcriptional profile of bone marrow mature neutrophils

We analyzed the impact of amoxicillin on the transcriptional profile of bone marrow mature neutrophils from infected mice withStreptococcus pneumoniae Overall design: Bone marrow mature neutrophils from amoxicillin (AMX)-treated infected mice (IAV/Sp/AMX)and infected mice left untreated (IAV/Sp) were sorted by FACS and analyzed using RNA-seq

本研究分析了阿莫西林对感染肺炎链球菌（Streptococcus pneumoniae）小鼠的骨髓成熟中性粒细胞转录组谱的影响。实验设计：分别通过流式细胞术分选（FACS）获取经阿莫西林（AMX）处理的感染小鼠（IAV/Sp/AMX组）与未接受治疗的感染小鼠（IAV/Sp组）的骨髓成熟中性粒细胞，并采用RNA测序（RNA-seq）进行转录组分析。