Additional file 2 of Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

Additional file 2: Table S1. CpG sites and relative weights (from Lighthart et al.) used to generate the DNAm CRP score. Table S2. SNPs and relative weights (from Dehghan et al.) used to generate the genetic score for CRP. Table S3. Summary of latent class analyses for log(CRP) and the DNAm CRP score in the Lothian Birth Cohort 1936. Table S4. Associations with determinants of CRP and the genetic CRP score. Table S5. Association between individual CpG sites and general cognitive ability (gf) in the Lothian Birth Cohort 1936 and Generation Scotland. Table S6. Longitudinal associations between the baseline DNAm CRP score and serum CRP and general cognitive ability (gf) over the four waves of follow-up in the Lothian Birth Cohort 1936.补充文件2：表S1。用于构建DNA甲基化CRP评分（DNAm CRP score）的CpG位点（CpG sites）及相对权重，数据源自Lighthart等人的研究。表S2。用于构建CRP遗传评分的单核苷酸多态性（SNPs，single nucleotide polymorphisms）及相对权重，数据源自Dehghan等人的研究。表S3。洛锡安出生队列1936（Lothian Birth Cohort 1936）中CRP对数转换值与DNAm CRP评分的潜类别分析概况。表S4。CRP及遗传CRP评分的影响因素关联分析结果。表S5。洛锡安出生队列1936与苏格兰世代队列（Generation Scotland）中单个CpG位点与一般认知能力（gf，general cognitive ability）的关联分析结果。表S6。洛锡安出生队列1936的四轮随访中，基线DNAm CRP评分与血清CRP及一般认知能力（gf）的纵向关联结果。