Inflammatory response has been identified as a molecular signature of high-risk Group A ependymoma (EPN). To better understand the biology of this phenotype and aid therapeutic development, transcript
Additional file 11: Table S3. (A) List of top 10 RELAFUS1 motifs in RELAFUS1 peaks in 293T-RELAFUS1 cells. (B) List of top 5 Rela motifs in Rela peaks in MEFs (C) List of DNA sequences identified as t
HIPPO-YAP/TAZ signaling has been implicated in supratentorial ependymoma formation from neural progenitor cells (NPC) in the brain, however, the underlying mechanisms to trigger the neural progenitor
Additional file 12: Table S4. (A) Dysregulated pathways driven by RELAFUS1target genes in TSS±10kb in 293T-RELAFUS1 cells. (B) Dysregulated pathways driven by RELAFUS1 target genes in TSS ±10kb in H12
Pediatric ependymoma is a devastating brain cancer marked by its relapsing pattern and lack of effective chemotherapies. This shortage of treatments is due to limited knowledge about ependymoma tumori
