Crystal structure of the human inducible form 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
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Crystal structure of the human inducible form 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Descriptor: 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)], ADENOSINE-5'-DIPHOSPHATE, ... Authors: Kim, S.G, Manes, N.P, El-Maghrabi, M.R, Lee, Y.H. Deposit date: 2005-09-05 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy. J.Biol.Chem., 281, 2006
人类诱导型6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶晶体结构
描述符:6-O-磷酸基-β-D-呋喃果糖、6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶3(6PF-2-K/Fru-2,6-P2ASE脑/胎盘型同工酶)(iPFK-2)【包含:6-磷酸果糖-2-激酶(EC 2.7.1.105);果糖-2,6-二磷酸酶(EC 3.1.3.46)】、腺苷-5'-二磷酸等
作者:Kim S.G、Manes N.P、El-Maghrabi M.R、Lee Y.H
沉积日期:2005-09-05
发布日期:2005-12-06
最后修改日期:2023-08-23
实验方法:X射线衍射(2.1 Å)
引用文献:缺氧诱导型6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶(PFKFB3)的晶体结构:一种潜在的癌症治疗新靶点。《生物化学杂志》,281卷,2006年
创建时间:
2005-09-05



