Whole transcriptome mapping identifies the non-coding RNA landscape remodeled by mechanical stress in OA-like chondrocytes (miRNA)

To explore the effects of mechanical stress on whole transcriptome landscape and to identify a non-coding transcriptome signature of mechanics response, next-generation RNA sequencing (RNA-seq) was performed on mouse OA-like chondrocytes stimulated by mechanical stress.

为探究机械应力对全转录组图谱的影响，并鉴定机械应答的非编码转录组特征，本研究对经机械应力刺激的小鼠骨关节炎（Osteoarthritis, OA）样软骨细胞开展了下一代RNA测序（RNA-seq）。