Meta-Analysis Identifies Pleiotropic Loci Controlling Phenotypic Trade-offs in Sorghum

This dataset includes genotype level trait values for 234 traits, some previously published and some unpublished, scored across the Sorghum Association Panel (SAP). It also includes all statistically significant GWAS hits identified when these same trait datasets were analyzed using either GLM, MLM, or FarmCPU GWAS algorithms as implemented in the MVP R package (https://github.com/xiaolei-lab/rMVP) with the genetic marker set first published in Miao et al 2020 (doi: https://doi.org/10.1104/pp.20.00277). The aggregated trait data and GWAS results deposited here were published as part of: <br>Mural RV, Grzybowski M, Miao C, Damke A, Sapkota S, Boyles RE, Salas-Fernandez MG, Schnable PS, Sigmon B, Kresovich S, Schnable JC (Preprint) "Meta-Analysis Identifies Pleiotropic Loci Controlling Phenotypic Trade-offs in Sorghum" doi: To Come.<br><br><br><br><br>

本数据集包含234个性状的基因型水平表型值，其中部分性状已发表，部分尚未发表，所有性状均在高粱关联作图群体（Sorghum Association Panel, SAP）中完成表型打分。本数据集还包含当采用MVP R包（https://github.com/xiaolei-lab/rMVP）中实现的广义线性模型（General Linear Model, GLM）、混合线性模型（Mixed Linear Model, MLM）或FarmCPU全基因组关联分析（Genome-Wide Association Study, GWAS）算法，对上述性状数据集进行分析时，所鉴定出的全部具有统计学显著性的GWAS关联位点；本次分析所用的遗传标记集首次发表于Miao等人2020年的研究（DOI: https://doi.org/10.1104/pp.20.00277）。本数据集所收录的整合性状数据与GWAS结果，已作为以下预印本的一部分发表：<br>Mural RV、Grzybowski M、Miao C、Damke A、Sapkota S、Boyles RE、Salas-Fernandez MG、Schnable PS、Sigmon B、Kresovich S、Schnable JC（预印本）《元分析鉴定出调控高粱表型权衡的多效性位点》，DOI待刊。