PPTC RNAseq and Genomic Alterations

Data deposited here have origins through the National Cancer Institute Pediatric Preclinical Testing Consortion (NCI PPTC) and Alex's Lemonade Stand.<br>The RNAseq data is an FPKM matrix of 250 samples measured across 51,968 genes.<br>The alterations matrix consist of deleterious DNA mutations, DNA copy number alterations, and fusions of varying functional confidence.<br>Gene expression classifiers are applied to the gene expression matrix and the results are interpreted in https://github.com/marislab/pdx-classification

本数据集所存数据源自美国国家癌症研究所儿科临床前测试联盟（National Cancer Institute Pediatric Preclinical Testing Consortium, NCI PPTC）以及亚历克斯柠檬水公益组织（Alex's Lemonade Stand）。<br>本数据集所含RNA测序（RNAseq）数据为FPKM表达矩阵，涵盖250个样本、51968个基因的表达量检测结果。<br>该变异特征矩阵包含有害DNA突变、DNA拷贝数变异以及功能可信度各异的基因融合事件。<br>研究人员将基因表达分类器应用于该基因表达矩阵，相关结果的解读可参见https://github.com/marislab/pdx-classification