PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000811b

PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000811b Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-hydroxybenzonitrile, Tyrosine-protein phosphatase non-receptor type 1 Authors: Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. Deposit date: 2018-08-30 Release date: 2018-10-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.07 Å) Cite: An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018

PanDDA分析组存档数据——与compound_FMSOA000811b结合的蛋白酪氨酸磷酸酶1B（PTP1B）晶体结构。描述项：2-氨基-2-羟甲基-丙烷-1,3-二醇（2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL）、邻羟基苯甲腈（2-hydroxybenzonitrile）、非受体型酪氨酸蛋白磷酸酶1B（Tyrosine-protein phosphatase non-receptor type 1）。作者：Keedy, D.A、Hill, Z.B、Biel, J.T、Kang, E、Rettenmaier, T.J、Brandao-Neto, J、von Delft, F、Wells, J.A、Fraser, J.S。存档日期：2018-08-30；发布日期：2018-10-10；最后修改日期：2024-03-06。实验方法：X射线衍射（分辨率2.07 Å）。引用文献：《基于多温度晶体学、片段筛选与共价锚定技术解析PTP1B的扩展变构网络》，Elife，第7卷，2018年。