M1 microglia disrupt the barrier function of retinal microvascular endothelial cells via ANGPT2/TIE2 axis

Human microglial clone 3 cells (HMC3) was induced to M1 or M2 status, then co-cultured with retinal microvascular endothelial cells (hRMECs) in vitro.将人类小胶质细胞克隆3株（HMC3）诱导至M1或M2状态，随后在体外与视网膜微血管内皮细胞（hRMECs）进行共培养。