Polymorphisms identified in UNC Nigerian F5 Group 1.

Data from direct sequencing of Group 1 individuals are summarized. Polymorphic nucleotides are indicated in lower case, with flanking and intervening nucleotides in upper case. Nucleotides absent from an allele (i.e. indel polymorphism) are represented by an equivalent number of dashes. Where a single SNP, multi-nucleotide polymorphism or indel polymorphism was found, the variants are shown within the same sequence expression. For amplicons with more than one polymorphic region, the genotype of each allele is listed individually. Where additional polymorphic regions were found in other datasets but were not polymorphic in the dataset in question, the genotypes at the additional variant positions are shown in parentheses. Primer regions were excluded when determining the number of base pairs screened for each amplicon. The positions of the polymorphic nucleotides are given as positions within the full amplicon sequence, including primer regions. Full genotype ratios recovered in the dataset are given for all genes except hhex, where two genotypes arising from allelic dropout are omitted for brevity. Abbreviations: bp, base pairs; cds, coding sequence; nt, nucleotide; UTR, untranslated region.

本数据集汇总了第1组个体的直接测序数据。多态性核苷酸以小写字母标注，侧翼及间隔核苷酸以大写字母标注。等位基因缺失的核苷酸（即插入缺失多态性）以相同数量的短横线表示。当存在单核苷酸多态性（single nucleotide polymorphism, SNP）、多核苷酸多态性或插入缺失多态性时，所有变异将在同一序列表达式中展示。对于包含多个多态性区域的扩增子（amplicon），将分别列出每个等位基因的基因型。若在其他数据集中共发现额外多态性区域，但在本数据集中未表现出多态性，则额外变异位点的基因型将以括号标注。在计算每个扩增子的筛查碱基对数量时，引物区域将被排除在外。多态性核苷酸的位置以包含引物区域在内的完整扩增子序列内的位置标注。本数据集所获全部基因的完整基因型比例均已列出，仅hhex基因除外：为行文简洁，该基因中因等位基因脱扣产生的两种基因型未予列入。缩写说明：bp（base pairs，碱基对）；cds（coding sequence，编码序列）；nt（nucleotide，核苷酸）；UTR（untranslated region，非翻译区）。