Current Qualified and Proposed Kidney Biomarkers.

aBiomarkers are referenced by their most common referenced Human gene name followed by the official rat gene symbol in parentheses.
bKidney injury locations include proximal tubules (Prox Tub), distal tubules (Dist Tub), loop of henle (Lp Hnle).
cWhere genes did not meet filter criteria for inclusion in list of DEGs, reasons are shown: insufficient fold change (low FC) or high variability (high var).
dMaximum fold change distance within the life cycle is shown.

a. 生物标志物以其最常用的人类基因名称标注，随后在括号内附上官方大鼠基因符号。
b. 肾脏损伤部位包括近端小管（Prox Tub）、远端小管（Dist Tub）以及亨利袢（Lp Hnle）。
c. 若基因未达到纳入差异表达基因（Differentially Expressed Genes，DEGs）列表的筛选标准，则会标注具体原因：折叠变化幅度不足（低FC）或变异程度偏高（高var）。
d. 本数据集展示了生命周期内的最大折叠变化差值。