SH1037432.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE为界定、识别、传播及开展基于DNA的物种假说（DNA-based Species Hypotheses，SH）相关研究提供了统一的解决方案。国际核苷酸序列数据库中的全部真菌内部转录间隔区（Internal Transcribed Spacer，ITS）序列，通过应用一组动态距离阈值（0.5%至3.0%），被聚类至近似物种水平的分类单元。所有基于DNA的物种假说均被赋予唯一且稳定的、采用数字对象标识符（Digital Object Identifier，DOI）格式的名称，其分类学与生态学注释信息将通过分布式、基于网页的第三方注释工作完成审核验证。物种假说（SH）将尽可能结合该假说下所有序列的鉴定结果，与对应分类单元名称及其分类层级（如门、纲、目等）建立关联。系统将为每个此类物种假说选取一条自动或人工指定的序列作为代表序列，这些代表序列已发布于（https://unite.ut.ee/repository.php），可供科学界用于本地序列相似性搜索、下一代测序分析流程等研究场景。随着公共真菌ITS序列数量的持续增长，该系统与相关数据将自动完成更新。