Transplanted pluripotent stem cell derived-islets engraft superior to human islets

To investigate gene expression differences between human stem cell-derived islets and human islets before transplantation. We performed gene expression profiling analysis using data obtained from RNA-seq of 5 different batches of stem cell-derived islets and human islets from 7 donors. Overall design: Comparative gene expression profiling analysis of RNA-seq data for stem cell-derived islets (sample A-E) and human islet donors (sample I-VII)).

本研究旨在探究移植前人干细胞源性胰岛（stem cell-derived islets）与供体来源人胰岛之间的基因表达差异。我们采用RNA测序（RNA-seq）数据开展基因表达谱分析，所用数据来自5批不同批次的干细胞源性胰岛，以及7名供体的人胰岛样本。实验整体设计：针对干细胞源性胰岛（样本A~E）与供体来源人胰岛（样本I~VII）的RNA测序数据开展对比基因表达谱分析。