Gene profiling of young rats susceptible to malaria infection

The study was performed in order to determine molecular markers potentially involved in the susceptibility of young rats to the infection with Plasmodium berghei Anka In this study, we compared the microarrays of spleens (using the rat Codelink developed by Amersham Biosources) obtained from young rats infected by Plasmodium berghei Anka with those of uninfected age matched controls.

本研究旨在鉴定可能与幼年大鼠感染伯氏疟原虫安卡株（Plasmodium berghei Anka）易感性相关的分子标志物。本研究中，我们将感染伯氏疟原虫安卡株的幼年大鼠的脾脏微阵列（采用安玛西亚生物源（Amersham Biosources）开发的大鼠Codelink芯片）与未感染的同龄对照大鼠的脾脏微阵列进行了比较。