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Novel non-HLA loci associated with SSc clinical and serological subtypes.

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https://figshare.com/articles/dataset/_Novel_non_HLA_loci_associated_with_SSc_clinical_and_serological_subtypes_/427333
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†P values for GWAS cohorts are Mantel-Haenszel meta-analysis GC corrected according to the set λ and in the replication and combined analysis Mantel-Haenszel meta-analysis P value. *Association in rs11171747 had a significant BD P value, thus making it heterogeneous association among populations.

† 全基因组关联研究(Genome-Wide Association Study, GWAS)队列的P值为依据设定的λ值完成基因组校正(Genomic Control, GC)的曼特尔-亨塞尔(Mantel-Haenszel)荟萃分析结果,且在验证分析与合并分析中均采用曼特尔-亨塞尔荟萃分析得到的P值。 * rs11171747位点的关联分析获得了具有统计学显著性的双相障碍(Bipolar Disorder, BD)相关P值,进而提示该位点在不同人群中存在异质性关联。
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2011-07-14
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