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Mean plasma and brain levels of CoQ10, in 10-week old mice, after 6 w of treatment.

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https://figshare.com/articles/dataset/_Mean_plasma_and_brain_levels_of_CoQ10_in_10_week_old_mice_after_6_w_of_treatment_/528920
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Plasma: Both R6/2 and WT treated mice had higher levels than untreated mice. Treatment main effect: F(1,16) = 173.5, p<0.0001). Treated, but not untreated, mutant mice had higher plasma levels than WT mice (genotype main effect: F(1,16) = 6.1, p<0.026; genotype×treatment interaction: F(1,16) = 6.0, p<0.02, simple main effects: p<0.05). Levels were higher in females than male mice (gender main effect: F(1,16) = 15.7, ps<0.02). Brain: CoQ10 levels in animals receiving 0.6% CoQ10 were higher than those of untreated mice, independent of gender and genotype (treatment main effect: F(1,16) = 15.8, p<0.01).

血浆:R6/2与野生型(Wild Type, WT)经处理的小鼠,其血浆指标水平均高于未处理小鼠。处理主效应:F(1,16)=173.5,p<0.0001。经处理而非未处理的突变型小鼠,其血浆指标水平高于野生型小鼠(基因型主效应:F(1,16)=6.1,p<0.026;基因型×处理交互效应:F(1,16)=6.0,p<0.02;简单主效应:p<0.05)。雌性小鼠的指标水平高于雄性小鼠(性别主效应:F(1,16)=15.7,p<0.02)。 脑组织:摄入0.6%辅酶Q10(Coenzyme Q10, CoQ10)的受试动物,其脑组织中CoQ10水平高于未处理小鼠,且该差异不受性别与基因型影响(处理主效应:F(1,16)=15.8,p<0.01)。
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2013-02-21
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