Data associated with Kotah and Rust et al.: Beyond the nuclear border: single-cell analysis of in situ sequenced human brain tissue using cellular features.

This upload includes data associated with the manuscript "Beyond the nuclear border: single-cell analysis of in situ sequenced human brain tissue using cellular features," which is a manuscript we wrote investigating different segmentation approaches for the analysis of in situ sequencing spatial transcriptomics data using the 10X Genomics Xenium platform. This paper was recently accepted at Communications Biology, and is accessible at https://doi.org/10.1038/s42003-025-08518-6. Analysis codes can be accessed at: https://github.com/jmkotah/xenium_segmentation_paper. Data are uploaded as ZIP files to preserve the folder structure used in the analysis. Please get in touch should there be any issues.本次上传包含与论文《超越核边界：基于细胞特征的原位测序（in situ sequencing）人脑组织单细胞分析》相关的数据。该论文为本团队撰写的研究成果，旨在探索采用10X Genomics Xenium平台分析原位测序空间转录组学（spatial transcriptomics）数据的不同分割方法。本论文近期已被《通讯生物学（Communications Biology）》接收，可通过链接https://doi.org/10.1038/s42003-025-08518-6访问。分析代码可通过https://github.com/jmkotah/xenium_segmentation_paper获取。为保留分析过程中使用的文件夹结构，数据以ZIP压缩包形式上传。若存在任何问题，欢迎随时联系。