EC-8P

EC-8P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection. The identification of the sample EC-8P: E: Denotes the strain ST-37 of Clostridioides difficile. C: Represents timepoint 2, indicating sampling after C. difficile infection. 8: Refers to the specific mouse number under investigation. P: Indicates the treatment administered, which in this case is Lactobacillus paracaseEC-8P数据集旨在探究副干酪乳杆菌（Lactobacillus paracasei）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。研究人员对感染后的小鼠粪便样本采用Invitrogen进行前处理，并于Ion Torrent NGS系统上完成测序。通过Ion Reporter SW（16S）开展分析后发现，在感染后第1、3、6天，微生物类群的动态特征发生显著变化，该研究为阐明益生菌在艰难梭菌感染期间调控肠道菌群的潜在价值提供了重要参考。 样本EC-8P的标识含义如下： E：代表艰难梭菌菌株ST-37； C：表示时间点2，即艰难梭菌感染后采样的时间节点； 8：指代本次研究中的特定小鼠编号； P：表示所施加的干预措施，本研究中为副干酪乳杆菌（Lactobacillus paracasei）。