Studies that molecular analyses were conducted.

BackgroundThis systematic literature analysis discusses cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL) in Türkiye, emphasizing the increasing importance of species determination studies and epidemiological research due to the emergence of new causative agents post-2010. It highlights the influx of immigrants and refugees into Türkiye, particularly from the neighboring countries where conflict occur.Materials and methodsThe study conducted a systematic review of research on leishmaniasis among refugees/immigrants in Türkiye between 2010 and 2022. A search in literature was carried out via English (PubMed, Scopus and Web of Science) and Turkish (TRDizin, and Council of Higher Education Thesis Center) databases published between 1 January 2010 and 31 December 2022. Two reviewers assessed the full-text articles to determine final eligibility.ResultsA total of 1,356 studies were identified, and 20 studies for CL, two studies for CL/VL and one study for VL (23 studies, 25 data set) were included in this systematic review. In these 22 studies, a total of 4,337 positive CL cases were reported. Among these positives 1,381 cases were diagnosed in Turkish individuals. The remaining 2,956 positive CL cases were the immigrants from different countries including Syria (n=2,925), Iraq (n=13), Afghanistan (n=7), Somalia (n=4), Iran (n=3) and one case each of Libya, Turkmenistan, Tunisia and Morocco. We also identified the presence of 94 positive visceral leishmaniasis cases, with 75 cases being among Turkish individuals and 19 cases among Syrian refugees in three studies.ConclusionsThe systematic review underscores the significance of international epidemiological data sharing and robust health monitoring systems to manage the global public health threat posed by leishmaniasis and other infectious diseases related to population movements.背景 本系统文献分析针对土耳其（Türkiye）境内的皮肤利什曼病（cutaneous leishmaniasis, CL）与内脏利什曼病（visceral leishmaniasis, VL）展开讨论，着重阐述2010年后新型致病病原体出现的背景下，虫种鉴定研究与流行病学调查的重要性日益凸显。同时，本分析着重指出大量移民与难民涌入土耳其的现状，尤其是来自周边冲突频发国家的群体。 材料与方法 本研究对2010年至2022年间土耳其境内难民与移民群体的利什曼病相关研究开展系统综述。检索范围涵盖2010年1月1日至2022年12月31日发表于英文数据库（PubMed、Scopus及Web of Science）与土耳其语数据库（TRDizin、Council of Higher Education Thesis Center）的文献。由两名审阅者对全文文献进行最终资格评估以确定纳入标准。 结果 本研究共检索到1356项相关研究，最终纳入23项研究（含25个数据集），涵盖皮肤利什曼病相关研究20项、CL与VL共患相关研究2项及内脏利什曼病相关研究1项。其中22项研究共报告4337例皮肤利什曼病病原学阳性病例，其中1381例为土耳其本土个体确诊病例，剩余2956例为境外移民阳性病例，来源包括叙利亚（2925例）、伊拉克（13例）、阿富汗（7例）、索马里（4例）、伊朗（3例），以及利比亚、土库曼斯坦、突尼斯、摩洛哥各1例。此外，本研究还在3项研究中发现94例内脏利什曼病病原学阳性病例，其中75例为土耳其本土个体，19例为叙利亚难民。 结论 本系统综述强调，为应对利什曼病及其他与人口流动相关传染病构成的全球公共卫生威胁，亟需建立国际流行病学数据共享机制与健全的健康监测体系。