Biliary atresia and other pediatric cholestatic diseases

The dataset consisted of 2,759 ultrasound images obtained from 1,019 infants diagnosed with cholestatic diseases. This included 377 biliary atresia cases (664 fasting and 328 post-prandial images) and 642 non-BA cases (1,004 fasting and 580 post-prandial images). Additionally, there were 183 images documenting abnormal ultrasonographic findings such as triangular cord sign, dilated hepatic artery, and hilar hepatic cysts. Serum biochemical indicators including total bilirubin (TBIL), direct bilirubin (DBIL), gamma-glutamyl transpeptidase (GGT), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and total bile acids (TBA) were also collected. The study implemented nnU-Net to perform automated gallbladder segmentation across both fasting and postprandial ultrasound examinations. The configuration file (dataset.json) and the cross-validation results (5-fold) with detailed segmentation performance metrics were also provided.本数据集共包含2759张超声图像，均采集自1019名确诊为胆汁淤积性疾病的婴幼儿。其中包括377例胆道闭锁（biliary atresia）病例（含664张空腹超声图像与328张餐后超声图像）以及642例非胆道闭锁病例（含1004张空腹超声图像与580张餐后超声图像）。此外，数据集还包含183张记录异常超声表现的图像，其表现包括三角索征、肝动脉扩张及肝门部肝囊肿等。同时采集了受试者的血清生化指标，包括总胆红素（total bilirubin, TBIL）、直接胆红素（direct bilirubin, DBIL）、γ-谷氨酰转移酶（gamma-glutamyl transpeptidase, GGT）、丙氨酸氨基转移酶（alanine aminotransferase, ALT）、天冬氨酸氨基转移酶（aspartate aminotransferase, AST）、碱性磷酸酶（alkaline phosphatase, ALP）及总胆汁酸（total bile acids, TBA）。本研究采用nnU-Net对空腹及餐后超声图像中的胆囊进行自动分割。此外还提供了配置文件（dataset.json）以及包含详细分割性能指标的5折交叉验证结果。