Additional file 6 of Identification and ranking of recurrent neo-epitopes in cancer

Additional file 6 Expected number of target patients for each neo-epitope candidates, for the 18 cancer entities with associated epidemiological data. The expected number of patients is the product between the number of new cases, the observed variant frequency and the HLA type frequency in the US population. The total expected number of patients for each candidate is the sum over the expected number of candidates by study.

附加文件6 记录了18个配有流行病学数据的癌种中，各新表位候选体（neo-epitope candidates）对应的预期靶标患者数量。预期患者数为新发病例数、观测到的变异频率与美国人群中HLA（Human Leukocyte Antigen）类型频率三者的乘积。每个候选体的总预期患者数为各研究对应的预期患者数之和。