Cryo-electron microscopy structure and densities of a pentameric ligand-gated ion channel GLIC

This Dataset contains cryo-electron microscopy (cryo-EM) densities and a pdb model of a Gloeobacter violaceus ligand-gated ion channel (GLIC). The densities were generated with RELION data processing software and the model was built with COOT software. Additionally the dataset contains a validation report generated by PDB/EMDB deposition webpage, where the data has been uploaded and is currently on hold until publication of the paper (https://deposit-pdbe.wwpdb.org/deposition). The densities, the model and the validation report were requested by reviewers for a publication titled 'Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM' currently accesible on Biorxiv and under review at eLife.本数据集包含紫色嗜蓝杆菌配体门控离子通道（Gloeobacter violaceus ligand-gated ion channel, GLIC）的冷冻电子显微镜（cryo-electron microscopy, cryo-EM）密度图与PDB模型。上述密度图通过RELION数据处理软件生成，模型则由COOT软件构建。此外，本数据集还包含由PDB/EMDB提交网页生成的验证报告，相关数据已上传至该平台，目前暂存，待论文发表后正式公开（提交链接：https://deposit-pdbe.wwpdb.org/deposition）。 本数据集的密度图、模型与验证报告由对应学术论文的审稿人索求，该论文题为《通过整合模拟与冷冻电镜技术发现配体门控离子通道的脂质结合位点》，目前可在BioRxiv平台公开获取，且正在eLife期刊接受同行评审。