DNA methylation status compared between asthma cases and controls in the BAMSE cohort (n = 546) using adjusted linear regression models.

*Only homozygous carriers of the allele (rs2168891) creating a CpG site were included in the analyses of CpG site 1 (Asthma ever n cases/controls = 236/234, Allergic asthma n cases/controls = 120/234, Non-allergic asthma n cases/controls = 116/234, Current asthma n cases/controls = 103/234).**Only homozygous carriers of the allele (rs2168890) creating a CpG site were included in the analyses of CpG site 2 (Asthma ever n cases/controls = 196/201, Allergic asthma n cases/controls = 94/201, Non-allergic asthma n cases/controls = 201/201, Current asthma n cases/controls = 89/201).†p-value for crude linear regression model.††p-value for linear regression model adjusted for gender, age at blood sampling and plate used for sodium-bisulfite treatment.*仅携带可形成CpG位点的rs2168891等位基因的纯合携带者，被纳入CpG位点1的相关分析（终身哮喘：病例/对照数=236/234；过敏性哮喘：病例/对照数=120/234；非过敏性哮喘：病例/对照数=116/234；当前哮喘：病例/对照数=103/234）。**仅携带可形成CpG位点的rs2168890等位基因的纯合携带者，被纳入CpG位点2的相关分析（终身哮喘：病例/对照数=196/201；过敏性哮喘：病例/对照数=94/201；非过敏性哮喘：病例/对照数=201/201；当前哮喘：病例/对照数=89/201）。† 未校正线性回归模型的p值。†† 经性别、采血年龄及亚硫酸氢钠处理所用板型校正的线性回归模型的p值。