Crystal Structure of Chimaeric Bcl2-xL and Phenyl Tetrahydroisoquinoline Amide Complex
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Crystal Structure of Chimaeric Bcl2-xL and Phenyl Tetrahydroisoquinoline Amide Complex Descriptor: 1-(2-{[(3S)-3-(aminomethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-4-chloro-5-methyl-N,N-diphenyl-1H-pyrazole-3-carboxamide, APOPTOSIS REGULATOR BCL-2 Authors: Porter, J, Payne, A, de Candole, B, Ford, D, Hutchinson, B, Trevitt, G, Turner, J, Edwards, C, Watkins, C, Whitcombe, I, Davis, J, Stubberfield, C, Fisher, M, Lamers, M. Deposit date: 2008-11-13 Release date: 2008-12-09 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Tetrahydroisoquinoline Amide Substituted Phenyl Pyrazoles as Selective Bcl-2 Inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
嵌合型Bcl2-xL与苯基四氢异喹啉酰胺复合物的晶体结构描述符：1-(2-{[(3S)-3-(氨甲基)-3,4-二氢异喹啉-2(1H)-基]羰基}苯基)-4-氯-5-甲基-N,N-二苯基-1H-吡唑-3-甲酰胺，细胞凋亡调控因子BCL-2
作者：Porter, J、Payne, A、de Candole, B、Ford, D、Hutchinson, B、Trevitt, G、Turner, J、Edwards, C、Watkins, C、Whitcombe, I、Davis, J、Stubberfield, C、Fisher, M、Lamers, M
入库日期：2008-11-13
发布日期：2008-12-09
最后修改日期：2024-05-08
实验方法：X射线衍射（2.1 Å）
引用文献：四氢异喹啉酰胺取代苯基吡唑类选择性Bcl-2抑制剂. 生物有机与药物化学快报（Bioorg.Med.Chem.Lett.）, 19, 2009
创建时间：
2008-11-13
