Extracellular proteins from Lactobacillus acidophilus are essential immunomodulatory players in Crohn Disease

In this study, the response of human immune cells to the extracellular proteins secreted by L. acidophilus is adressed. RNASeq is used to show how these proteins are able to shift the global immune response in Monocyte-derived dendritic cells.

本研究探讨了人类免疫细胞对嗜酸乳杆菌（L. acidophilus）分泌的细胞外蛋白的应答反应。研究采用RNA测序（RNASeq）技术，阐明了上述蛋白如何重塑单核细胞衍生树突状细胞的整体免疫应答。