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Gut microbiome-derived ammonia modulate intestinal motility in the host

NIAID Data Ecosystem2026-05-02 收录

微生物组-宿主互作

便秘机制研究

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP553593 数据链接链接失效反馈

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资源简介：

metagenomic sequencing of fecal samples from constipated mice

便秘小鼠粪便样本的宏基因组测序（metagenomic sequencing）

应用场景：

创建时间：

2025-01-29

微生物组-宿主互作

葡萄糖稳态调控

Gnotobiotic mice have been mono- and bi-colonized with Prevotella copri and Bacteroides thetaiotaomicron to study the affect of those bacteria on mouse glucose homeostasis. Total RNA was extrcated fro

NIAID Data Ecosystem60

Differential gene expression between L1 and L3.

微生物组-宿主互作

差异基因表达分析

Result of the differential gene expression analysis between the microbiome group defined as ‘L. crispatus’ (L1) and ‘Gardnerella’ (L3). Sheets 1 and 2 contain the top 15 most upregulated and downregul

Figshare2025-11-11 更新20

Transcriptome sequencing

基因表达调控

便秘机制研究

Sample source: mice intestineKey Methods:Oligo(dT) mRNA enrichmentFragmentation (~300 bp)Library size selection (~450 bp)Study Goal: Investigate transcriptional regulation of drugs that relieve consti

NIAID Data Ecosystem00

Airway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

慢性阻塞性肺疾病（COPD）

微生物组-宿主互作

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unkn

NIAID Data Ecosystem30

Table_4_Staphylococcus epidermidis isolates from atopic or healthy skin have opposite effect on skin cells: potential implication of the AHR pathway modulation.xlsx

微生物组-宿主互作

特应性皮炎机制研究

IntroductionStaphylococcus epidermidis is a commensal bacterium ubiquitously present on human skin. This species is considered as a key member of the healthy skin microbiota, involved in the defense a

NIAID Data Ecosystem20

Gut microbiome-derived ammonia modulate intestinal motility in the host

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