Genome-wide expression profiling of nematode-trapping fungus Arthrobotrys oligospora ku70 and ste12 strains upon nematode exposure

We report the transcriptomic comparisions between ku70 control and ste12 mutant strains in nematode-trapping fungus Arthrobotrys oligospora when induced with nematodes. Fungal Ste12 transcription factor and the upstream MAPK cascade are highly conserved and plays a role in host sensing and pathogenesis in various fungal pathogens. Identification of Ste12-dependent in A. oligospora may provide further insights into the molecular mechanisms of nematode-sensing and trap morphogenesis. The reference assemly used for remapping is A. oligospora TWF154 (GenBank assembly accession: GCA_004768765.1) Overall design: Examination of the transcriptional regulation controlled by Ste12 transcription factor upon nematode contact in Arthrobotrys oligospora

本数据集报道了捕食线虫真菌少孢节丛孢（Arthrobotrys oligospora）经线虫诱导后，ku70对照株与ste12突变株的转录组比较结果。真菌Ste12转录因子及其上游丝裂原活化蛋白激酶（MAPK）级联反应高度保守，在多种真菌病原菌的宿主识别与致病过程中发挥关键作用。鉴定少孢节丛孢中Ste12依赖的转录调控事件，可为解析线虫识别与捕器形态发生的分子机制提供进一步的研究见解。用于序列重比对的参考基因组组装版本为少孢节丛孢TWF154（GenBank组装登录号：GCA_004768765.1）。实验整体设计：探究少孢节丛孢在与线虫接触后，Ste12转录因子所调控的转录调控过程。