Gene ontology term of differentially expressed genes.

Five most significant GO terms for Gene Ontology term analysis of differentially expressed gene set in cerebral malaria isolates and 3D7-Lib compared to asymptomatic malaria isolates and 3D7 clone, respectively. The reported p-values are based on the “OddsRatio score”, a measure of gene-enrichment. Benjamini & Hochberg false discovery rate control procedure was applied to correct for multiple comparisons. CMT, cerebral malaria-associated parasites, trophozoite stage; AMT, asymptomatic carrier-associated parasites, trophozoite stage; 3D7-Lib T, trophozoite stage of 3D7-Lib line; 3D7 T, trophozoite stage of 3D7; 3D7-Lib R, ring stage of 3D7-Lib line; 3D7 R, ring stage of 3D7.
Gene ontology term of differentially expressed genes.

针对脑型疟分离株与3D7-Lib株、无症状疟分离株与3D7克隆株的差异表达基因集，分别开展基因本体（Gene Ontology，GO）富集分析，共获得5个统计学上最显著的GO术语。本次报告的P值基于优势比得分（OddsRatio score），该指标用于衡量基因富集水平。研究采用本雅明-霍赫贝格（Benjamini & Hochberg）错误发现率校正流程，以完成多重比较校正。各样本缩写释义如下：CMT：脑型疟相关寄生虫滋养体阶段；AMT：无症状携带者相关寄生虫滋养体阶段；3D7-Lib T：3D7-Lib株的滋养体阶段；3D7 T：3D7株的滋养体阶段；3D7-Lib R：3D7-Lib株的环状体阶段；3D7 R：3D7株的环状体阶段。本数据集为差异表达基因的基因本体分析结果。