ATN072 Virology Results Form [CRF 12] Dataset in Computer-Delivered Motivational Intervention to Prevent Adherence Problems Among Youth Newly Recommended for HIV Medications: Project MESA (Motivational Enhancement System for Adherence)

Data from Virology Results Form [CRF 12]
Study Description
A two-phase study with the primary objective of adapting and piloting Motivational Enhancement System for Adherence (MESA), a brief, two-session, computer-based motivational intervention to prevent adherence difficulties among youth newly recommended to begin HAART. Phase I pre-tested the feasibility and acceptability of the beta version of MESA with Motivational Enhancement System for Health (MESH), a nutrition and exercise control intervention. Following analysis of Phase I responses and further modification of the intervention, Phase II (a pilot randomized controlled trial) was initiated. Phase II tested a two-session MESA intervention, as well as MESH (the attention control), matched for dose and delivery format. HIV+ youth aged 16 to 24

病毒学结果表[CRF 12]相关数据
研究概况
本研究为两阶段研究，首要目标为适配并试点依从性提升动机系统（Motivational Enhancement System for Adherence, MESA）——一种简短的双场次计算机化动机干预手段，用于预防新推荐启动高活性抗反转录病毒治疗（Highly Active Antiretroviral Therapy, HAART）的青少年出现治疗依从性问题。第一阶段联合健康促进动机系统（Motivational Enhancement System for Health, MESH）对MESA的测试版开展可行性与可接受性预试验，其中MESH为营养与运动管控类对照干预措施。在对第一阶段的受试者反馈进行分析并对干预方案完成进一步优化后，研究启动了第二阶段，即一项试点随机对照试验。第二阶段对双场次的MESA干预方案，以及与方案剂量、实施形式均匹配的注意力对照干预MESH进行了效果评估。本研究的受试对象为16至24岁的HIV阳性青少年。