Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88Q mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88Q mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... Authors: Saran, S, Sanders, D.A.R. Deposit date: 2020-11-10 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.76 Å) Cite: THE ALLOSTERIC SITE RESIDUE, E88 INTERACTS WITH THE INHIBITORS TO TRANSMIT THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS BY FORMING A HYDROGEN BOND. To Be Published

空肠弯曲菌（C.jejuni）来源的二氢二吡啶甲酸合酶（Dihydrodipicolinate synthase, DHDPS）E88Q突变体，其活性位点结合丙酮酸，别构位点结合L-赖氨酸。
描述符：1,2-乙二醇、4-羟基四氢二吡啶甲酸合酶、乙酸根离子……
作者：Saran, S、Sanders, D.A.R.
沉积日期：2020-11-10
发布日期：2021-11-17
最后修改日期：2023-11-29
实验方法：X射线衍射（1.76埃）
引用文献："别构位点残基E88通过形成氢键与抑制剂相互作用，进而在空肠弯曲菌DHDPS中传递别构抑制信号"，待发表。