Transcriptome Analysis of rats with Chronic Unpredictable Mild Stress Treated with Electroacupuncture

RNA sequencing (RNA-Seq) was used to identify genome-wide alterations in the hippocampus of rats after chronic unpredictable mild stress (CUMS) and EA treatments to further elucidate the mechanism by which EA ameliorates depression to provide a basis for the clinical application of EA in stress - related diseases.

本研究采用RNA测序（RNA sequencing, RNA-Seq）技术，对经慢性不可预见性温和应激（chronic unpredictable mild stress, CUMS）造模并接受电针（Electroacupuncture, EA）干预的大鼠海马组织的全基因组表达改变进行鉴定，以期进一步阐明电针改善抑郁症状的作用机制，为电针在应激相关疾病中的临床应用提供理论依据。