SH1040616.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE提供了一套统一的解决方案，用于界定、识别、交流及开展基于DNA的物种假说（Species Hypotheses，以下简称SH）相关研究。国际核苷酸序列数据库中的所有真菌内转录间隔区（Internal Transcribed Spacer，以下简称ITS）序列，均通过应用一组动态距离阈值（范围为小于0.5%至3.0%）聚类至近似物种水平。所有物种假说均会被赋予唯一且稳定的数字对象标识符（Digital Object Identifier，简称DOI）格式名称，其分类学与生态学注释将通过分布式、基于网页的第三方注释工作完成审核验证。SH将尽可能结合该假说下全部序列的鉴定结果，关联至对应分类单元名称及其所属分类层级（如门、纲、目等）。研究人员会选取一条自动或人工指定的序列，作为每个此类SH的代表序列。上述代表序列已公开发布（https://unite.ut.ee/repository.php），可供科学界用于本地序列相似性搜索、下一代测序分析流程等科研场景。随着公共真菌ITS序列数量的持续增长，该系统及其收录的数据将自动完成更新。